Imaging • CT or MRI scan of the abdomen and MRI scan of the pelvis are both useful for determining the extent of cancer in the pelvis, the presence of ovarian disease and the presence of involved pelvic and aortic lymph nodes and liver metastases. • Chest x-ray. Endoscopy and Biopsy • The definitive diagnosis is made on an endometrial biopsy, which involves a small scraping of the uterus and is usually performed in the doctor's office. A dilation and curettage (D&C) is required for some women those who have biopsy-proven endometrial hyperplasia ( see Endometrial Cancer Precursors ), who have an insufficient specimen on an office biopsy or who can't have an endometrial biopsy done in the office because of a small cervical opening or discomfort.